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Comment by mohammedalkhatib64 on January 20, 2013 at 10:25am

Thank u

Comment by parveen on October 8, 2012 at 7:13am

Scientists Uncover Genetic Link for Uterine Fibroids

THURSDAY, Oct. 4 (Health Day News) -- Researchers who discovered genetic risk factors linked to uteri fibroid in white women say their findings will lead to new screening and treatment methods for the condition.

Uterine fibroids are the most common type of pelvic tumour in women -- they occur in 75 percent of women of reproductive age -- and the leading cause of hysterectomy the United States. Uterine fibroids can lead to abnormal vaginal bleeding, infertility pelvic pain and pregnancy complications.

Researchers at Brigham and Women's Hospital in Boston analyzed genetic data from more than 7,000 white women and identified variations in three genes that are significantly associated with uterine fibroids.

One of these variations occurred in a gene called FASN, which encodes a protein called FAS (fatty acid synthase). Further investigation showed that FAS protein production was three times higher in uterine fibroid samples compared to normal tissue, according to the report published online Oct. 4 in the American Journal of Human Genetics.

Overproduction of FAS protein occurs in various types of tumors and is believed to be important for tumor cell survival, the study authors pointed out in a hospital news release.

"Our discovery foretells a path to personalized medicine for women who have a genetic basis for development of uterine fibroids," senior study author Cynthia Morton, director of the Center for Uterine Fibroids, said in the news release. "Identification of genetic risk factors may provide valuable insight into medical management

Comment by Dahl Sagucio on September 25, 2012 at 9:22pm

Stem Cell Research – Man vs. God

Stem cells are the building blocks of life; they are the “Version 1.00″ of most cells of our body. All other cells (e.g. brain cells, blood cells, skin cells) are formed by the differentiation and maturation of these cells. The stem cells divide, mature and take on different functions based on the need. This is a process that occurs naturally when the embryo develops to a full term infant. These cells will continue to differentiate and integrate as a part of any other cell where it is transplanted.

Transplant these cells onto a site of injury, and the stage is set for potential healing and restoration of function.

How are these stem cells obtained?

Currently, the stem cells may be excavated from dead embryos, which were created solely “for the purpose of reproduction.” Adults also have a small percentage of stem cells in their bodies; these are found in the blood, in bone marrow, the brain, the liver and skin. There are 14 sites around the world that are recognized by the National Institute of Health Research as authorized suppliers of stem cells for research purposes. Research is currently being carried on to study the applicability of the stem cells in plastic surgery, in Parkinson’s disease and in spinal cord injury. People with spinal cord injuries may currently undergo the procedure of stem cell implantation in China or Portugal. There have been anecdotal reports of some functional gains after this surgery, but no published literature demonstrates significant improvement in independence.

see:
Stem Cell research

Comment by S.UMA DEVI on April 3, 2012 at 7:12pm

  CERVICAL CANCER SCREENING- AN UPDATE

Updated%20crvical%20cancer%20screening.docx

Comment by S.UMA DEVI on April 3, 2012 at 5:51pm

  ANTIBIOTICS IN RHINISINUSITIS

New%20Guidelines%20Stress%20Caution%20in%20Antibiotic%20Use%20for%2...

Comment by S.UMA DEVI on September 24, 2011 at 8:02pm

From Medscape Medical News
EMA: Restrict Terpenoid-Containing Suppositories in Children
Jim Kling

September 23, 2011 — The European Medicines Agency has changed its recommendations for suppositories that contain terpenic derivatives. It now says that they should not be used in children younger than 30 months or in children who have experienced febrile convulsion, epilepsy, or recent anorectal lesions.
Terpenic derivatives include turpentine, camphor, cineole, niaouli, wild thyme, terpineol, terpine, citral, menthol and essential oils of pine needle, and eucalyptus. They are commonly used to treat mild bronchial disorders, especially coughs.
The decision follows a review by the European Medicines Agency's Committee for Medicinal Products for Human Use (CHMP) that identified potential risks of terpenic derivatives. Among infants and small children, convulsions were a particular concern, along with other neurological disorders. The agents can also cause precancerous anorectal lesions, leading to the recommendation that children who have a recent history of such lesions should not receive these agents.
The CHMP review was prompted by the French medicines agency, which was particularly concerned about the potential for serious neurological adverse effects. The French agency carried out a risk–benefit assessment, which the CHMP considered in addition to information obtained from the manufacturers and marketers of suppositories that include terpenic derivatives.
Suppositories with terpenic derivatives are currently marketed in Belgium, France, Luxembourg, Finland, Italy, Portugal, and Spain.

Comment by S.UMA DEVI on September 4, 2011 at 8:12pm

RAPID DISGNOSTING TESTING OF INFECTIOUS DISEASES

From%20Medscape%20Infectious%20Diseases.doc

Comment by S.UMA DEVI on August 28, 2011 at 4:59am

 DAILY EXERCISE FOR 15 minutes

Moderate Exercise for 15 Minutes Daily Improves Survival

Laurie Barclay, MD

Authors and Disclosures

Physician Rating:      ( 25 Votes )             Rate This Article:   Top of Form Bottom of Form

August 19, 2011 — The minimal amount of physical activity to reduce mortality risk is 15 minutes a day of moderate-intensity exercise, according to the results of a prospective cohort study reported online August 16 in The Lancet.

"Exercising at very light levels reduced deaths from any cause by 14 percent," said senior author Xifeng Wu, MD, PhD, professor and chair of the University of Texas MD Anderson Cancer Center Department of Epidemiology, in a news release. "The benefits of exercise appear to be significant even without reaching the recommended 150 minutes per week based on results of previous research."

The study cohort consisted of 416,175 persons in Taiwan (199,265 men and 216,910 women) who were evaluated between 1996 and 2008 in a standard medical screening program. Average duration of follow-up was 8.05 ± 4.21 years. Participants were categorized according to the amount of weekly exercise self-reported on a questionnaire as inactive, low, medium, high, or very high activity. For each group, life expectancy and hazard ratios (HRs) were calculated for mortality risk, with use of the inactive group as the standard.

The average amount of exercise in the low-volume activity group was 92 minutes per week (95% confidence interval [CI], 71 - 112) or 15 ± 18 minutes per day. Risk for all-cause mortality was 14% lower (HR, 0.86; 95% CI, 0.81 - 0.91), and life expectancy was 3 years longer in the low-volume activity group vs the inactive group.

Beyond the minimal amount of 15 minutes of daily exercise, each additional 15 minutes was associated with a further reduction in all-cause mortality risk by 4% (95% CI, 2.5 - 7.0) and in all-cancer mortality risk by 1% (95% CI, 0.3 - 4.5). These benefits of exercise were seen in all age groups, in both sexes, and in persons at risk for cardiovascular disease. Compared with individuals in the low-volume group, inactive persons had a 17% increased risk for mortality (HR, 1.17; 95% CI, 1.10 - 1.24).

"15 min a day or 90 min a week of moderate-intensity exercise might be of benefit, even for individuals at risk of cardiovascular disease," the study authors write.

Limitations of this study include observational design with possible confounding, reliance on self-report to determine exercise amount, lack of generalizability to other populations, and possible loss to follow-up.

In an accompanying editorial, Anil Nigam and Martin Juneau, from Montreal Heart Institute and Université de Montréal in Quebec, Canada, note that "this is the first observational study of this size to report important and global health benefits at such a low volume of leisure-time physical activity with this degree of precision."

"The knowledge that as little as 15 min per day of exercise on most days of the week can substantially reduce an individual's risk of dying could encourage many more individuals to incorporate a small amount of physical activity into their busy lives," Drs. Nigam and Juneau write. "Governments and health professionals both have major roles to play to spread this good news story and convince people of the importance of being at least minimally active."

The exercise project was funded by the Taiwan Department of Health Clinical Trial and Research Center of Excellence, and the Taiwan National Health Research Institutes supported this study. The study authors and editorialists have disclosed no relevant financial relationships.

Lancet. Published online August 16, 2011.

Comment by S.UMA DEVI on August 28, 2011 at 4:44am

 NEWS ABOUT PPIs

 

 

From%20Medscape%20Medical%20News.doc

Comment by Mayar Shams El-din on August 1, 2011 at 5:20am

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