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HbA1c levels falsification in diabetes

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Permalink Reply by Ankala Subbarao on November 9, 2010 at 9:38am

Dear Madam
The discussion is missing!!

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Permalink Reply by S.UMA DEVI on November 9, 2010 at 4:34pm

thank you sir for the comment.
Actually i had put it up as apiece of information for the UGs and PGS
Any how, to start a discussion on this matter , Iwould be pleased to be enlightened as to how to correlate HbA1c levels and blood sugar values in such situations T

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Permalink Reply by Ankala Subbarao on November 9, 2010 at 8:55pm

Glycated hemoglobin (glycosylated hemoglobin, hemoglobin A1c, HbA1c, A1C, or Hb1c; sometimes also HbA1c) is a form of hemoglobin used primarily to identify the average plasma glucose concentration over prolonged periods of time. It is formed in a non-enzymatic glycation pathway by hemoglobin's exposure to plasma glucose. Normal levels of glucose produce a normal amount of glycated hemoglobin. As the average amount of plasma glucose increases, the fraction of glycated hemoglobin increases in a predictable way. This serves as a marker for average blood glucose levels, over the previous months prior to the measurement.

The 2010 American Diabetes Association Standards of Medical Care in Diabetes added the A1c ≥ 6.5% as another criterion for the diagnosis of diabetes, but this is controversial and has not been universally adopted.

In diabetes mellitus, higher amounts of glycated hemoglobin, indicating poorer control of blood glucose levels, have been associated with cardiovascular disease, nephropathy, and retinopathy. Monitoring the HbA1c in type-1 diabetic patients may improve treatment.

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Permalink Reply by Ankala Subbarao on November 9, 2010 at 8:57pm

Correlation of Hb A1C with Blood sugar values:

HbA1c eAG (estimated average glucose)
(%) (mmol/L) (mg/dL)
5 5.4 (4.2–6.7) 97 (76–120)
6 7.0 (5.5–8.5) 126 (100–152)
7 8.6 (6.8–10.3) 154 (123–185)
8 10.2 (8.1–12.1) 183 (147–217)
9 11.8 (9.4–13.9) 212 (170–249)
10 13.4 (10.7–15.7) 240 (193–282)
11 14.9 (12.0–17.5) 269 (217–314)
12 16.5 (13.3–19.3) 298 (240–347)

Source: Wikepedia.